Gene
erg
- ID
- ZDB-GENE-041212-40
- Name
- ETS transcription factor ERG
- Symbol
- erg Nomenclature History
- Previous Names
-
- erg1 (1)
- zgc:103429
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in angiogenesis and hemangioblast cell differentiation. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in myeloid leukemia. Is expressed in several structures, including angioblastic mesenchymal cell; cardiovascular system; intermediate cell mass of mesoderm; mesoderm; and pharyngeal arch. Orthologous to human ERG (ETS transcription factor ERG).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:103429 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Liu et al., 2008
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Lymphatic malformation 14 | 620602 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000418 | Ets domain |
| Domain | IPR003118 | Pointed domain |
| Family | IPR046328 | ETS family |
| Homologous_superfamily | IPR013761 | Sterile alpha motif/pointed domain superfamily |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Ets domain | ETS family | Pointed domain | Sterile alpha motif/pointed domain superfamily | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q5PR65
|
427 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids